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No dose adjustment is warranted. The decreased publicity of tadalafil with the coadministration of rifampin or other CYP3A4 inducers could be anticipated to reduce the efficacy of CIALIS for once every day use; the magnitude of reduced efficacy is unknown.
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CIALIS to be used as desired was revealed to further improve erectile function compared to placebo up to 36 hours next dosing. Therefore, when advising individuals on best utilization of CIALIS, this should be taken into consideration.
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